Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene.

Function

IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.

Interactions

IRAK2 has been shown to interact with TRAF6 and Myd88.

References

Further reading



IRAK2 Gene GeneCards IRAK2 Protein IRAK2 Antibody

Increased expression of the interleukin1 receptorassociated kinase

Inhibition of interleukin1 receptorassociated kinase 1 (IRAK1) as a

Interleukin1 ReceptorAssociated Kinase2 (IRAK2) Is a Critical

Interleukin1 regulates keratinocyte expression of T cell targeting